Derek Hoffman was the initial drummer in Chicago, Illinois death metallers Gorgasm. After his departure Gorgasm continued with Terence Manauis.
Derek Hoffman also played drums in Fleshgrind since May 2002, replacing previous drummer Alan Collado.
Hoffman left in 2004, to join ex-Gorgasm members Tom Angelos and Russ Powell (guitar and bass respectively). The three musicians formed Depths of Agony.
More recently Derek Hoffman played drums in Worms Inside, the band formerly known as Worms Inside You. The band, featuring guitarist Tom Tangalos (ex-Gorgasm) vocalist James Eads (Rellik) and bassist Jeremy Barger (Torn Between), parted ways with Hoffman in February 2006. The drummer was followed up by former Martyr drummer Max Colunga.